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The high stress circumstances may trigger depression and in adverse manner alter behavioral, learning, and biochemical activities. A mood disorder such as major depression is probable life endangering disease. A sizeable population Max synapse of patients with depression is reckoned to be treatment resistant even after advancement of pharmacotherapy. The antidepressant drugs suffer from drawbacks such as postcompliance side effects or absence of required effect. These findings have ignited the minds of researchers to pursue hunt for natural remedies for improved beneficial effects with no or lesser toxic consequences. The dementia is often manifested by Alzheimer’s disease. It causes severe suffering for the patients, in the form of Max synapse Brain progressive behavioral and neurological changes that include functional impairment, loss of independency, emotional problems, and behavioral disturbances 

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