Richard Gray's Blog (22)

CD Bioparticles, a leading manufacturer and supplier of numerous drug delivery products and services, has announced the launch of its Organoid Construct Kits to the scientific community to facilitate the construction of complex organoid models, enabling…

With years of experience in the pharmaceutical and life science sectors, CD Bioparticles is excited to announce the launch of its new line of Stable-Isotope Labeled Particles to the scientific community, providing scientists and researchers with a powerful…

CD Bioparticles, a leading manufacturer and supplier of numerous drug delivery products and services, is proud to announce its expanded capabilities in Customized Liposomes. This advancement allows researchers and developers to leverage the power of liposome technology for a wider…

With years of experience in the pharmaceutical and life science sectors, CD Bioparticles announces its advanced line of multiplex fluorescence particles designed to streamline complex biological assays in flow cytometry experiments. These particles exhibit low signal…

CD Bioparticles, a leading manufacturer and supplier of numerous drug delivery products and services, is pleased to announce the availability of Polystyrene Family polymers for a variety of drug delivery applications. These polymers offer tunable…

With years of experience in the pharmaceutical and life science sectors, CD Bioparticles is excited to announce the launch of its new line of Conjugated Agarose Particles with various particle sizes (45-500 µm), designed to streamline protein…

CD Bioparticles, a leading manufacturer and supplier of numerous drug delivery products and services, announced the launch of its expanded line of low-PDI polymers, Polyacrylamides. The new product line offers different functional groups (e.g., acid, amine, and methoxy) and a variety of molecular…

With years of experience in the pharmaceutical and life science sectors, CD Bioparticles proudly announces the launch of its latest product line of Agarose Particles for isolation and purification of proteins and antibodies. These versatile…

Traditional immunoassays based on the format of 96-well microtiter plates are widely used in analytical laboratories and have become increasingly automated with the introduction of robotics technology in recent years, thereby enhancing assay throughput. Most clinical analyzers essentially operate as “stand-alone laboratories,” featuring precise, accurate, and highly reproducible programmatic liquid handling, sample addition, and washing steps. However, aside from cost, the size limitations…

Many clinical trials of mRNA-based drugs or vaccines have failed to successfully pass Phase I or Phase II. The reasons behind this are various, including low efficacy of candidate drugs and lower-than-expected clinical risk/treatment benefit profiles. Preclinical safety assessments aim to identify well-tolerated and efficacious …

Poly(lactic-co-glycolic acid) (PLGA) is a functional polymer organic compound randomly polymerized by lactic acid (PLA) and glycolic acid (PGA). It has been approved by the U.S. Food and Drug Administration It is certified by the Food and Drug Administration (FDA) and is a copolymer material available on the market. PLGA…

What is POCT?

POCT (Point-of-Care Testing) refers to clinical and bedside testing conducted in close proximity to patients. It is often not performed by clinical laboratory personnel. POCT holds significant importance in disease prevention, etiology determination, prognosis, enhancing treatment outcomes, and reducing healthcare expenses. It meets clinical testing needs across various healthcare settings. POCT serves as a…

Antibody-drug conjugates (ADCs) are conjugated products of monoclonal antibodies (mAbs) and cytotoxic small molecules. In tumor treatment, although monoclonal antibodies have good targeting properties, most of them target extracellular or cell surface antigens, have weak anti-tumor activity, have limited therapeutic effect on solid tumors, and are more likely to develop drug resistance; conventional anti-tumor chemotherapy Although drugs have high anti-tumor cell activity, they lack…

What are Dyed Polystyrene Latex Particles?

Polystyrene particles (PSP) are commercially available in different sizes, ranging from 15 nanometers to several micrometers, with narrow size distributions and various surface chemistries. Additionally, polystyrene is generally considered inert and nontoxic, making it safe for use in a variety of biological assays. …

As a promising systemic drug delivery method, transdermal drug delivery system (TDDS) is easier and more convenient to operate than traditional oral, intravenous and subcutaneous injection methods. It can improve patient compliance while also avoiding First-pass effect and drug side effects. As the largest organ of the human body, the skin is also the body’s first line of…

What is Zeta Potential?

Zeta potential (ZP) is a physical property exhibited by any particle in a suspension, macromolecule or material surface. ZP is an analytical technique used to determine the surface charge of nanoparticles in colloidal solutions. The surface of a charged particle attracts and binds firmly to a thin layer of opposite charge, forming a thin layer of liquid…

Hydrogel is a three-dimensional network of hydrophilic polymers that swells in water without dissolving. Because the polymer contains a large number of hydrophilic groups, the hydrogel can absorb and lock a large amount of water. After absorbing water, the hydrogel network can maintain its original shape without being destroyed. Hydrogels are widely used in tissue engineering, drug delivery, biosensing, etc. due to their simple preparation, strong tunability of mechanical properties, good…

Surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS) are two key surface plasmon technologies that ultimately enable single-molecule-level chemical and biological sensors. Due to the tremendous progress in solution-based synthesis methods, plasmonic nanoparticles with various complex shapes (e.g., spheres, rods, and prisms) have been widely used for surface plasmon resonance and surface-enhanced Raman scattering sensing. Localized surface plasmon resonance (LSPR)…

Micelles refer to molecularly ordered aggregates that begin to form in large quantities after the surfactant concentration reaches a certain value in an aqueous solution. In micelles, the hydrophobic groups of surfactant molecules aggregate to form the core of the micelle, and the hydrophilic polar groups form the outer layer of the micelle. Liposomes are an artificial membrane. In the water, the hydrophilic head of the phospholipid molecule is inserted into the water, and the hydrophobic…

With the continuous development of nanotechnology, gold nanoparticles are widely used in the field of medicine. Gold nanoparticles not only have good controllability, biocompatibility, and biosorption, but also have a high degree of stability, and can achieve specific biometrics and functions through surface modification. Therefore, it has become an important nanomaterial in biomedicine.

The Role of Gold Nanoparticles…