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When injected into the eye, it reduces fluid leakage and interferes with the growth of new blood vessels in the retina.Today ongoing research supported by the National Eye Institute (NEI), United States, is looking into drugs that may stop the retina from sending signals Diabetes Free to the body to grow new blood vessels and so prevent diabetic retinopathy.What is diabetic ketoacidosis, what causes diabetic ketoacidosis? What are its signs and symptoms, how can or is diabetic ketoacidosis treated. What are the treatment guidelines? How does one prevent the condition? What about treatment in children? All these questions and more will be treated in this article.Diabetic Ketoacidosis (DKA) is a potentially life threatening condition of diabetes occurring mostly in patients with Type 1 diabetes but on occasion also in patients with Type 2 diabetes.

Patients suffering from the condition will characteristically experience the following; ketoacidosis, hyperglycaemia and ketonuria. DKA happens due to a shortage of insulin in the body and so because the body is no longer able to derive the energy it needs from blood sugar, it switches over to burning fat as the alternative energy source. This produces acidic ketones responsible for most of the complications of the condition.The most frequent early signs of Diabetic Ketoacidosis or DKA is a sharp increase in polydipsia and polyuria. Whilst Polydipsia means excessive thirst, Polyuria refers to the excessive production of dilute urine.Other symptoms include malaise, generalized weakness, and tiredness.

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These may then progress if untreated to vomiting, deep gasping breathing (kussmaul respiration), dehydration, rapid weight loss in patients newly diagnosed with Type 1 diabetes, mild disorientation, confusion and occasionally coma.Diabetic ketoacidosis occurs in 4.6-8.0% of people with type 1 diabetes annually. In the United States, 135,000 hospital admissions occur annually as a result of DKA at an estimated cost of a quarter to a half of the total cost of caring for people with type 1 diabetes-that's a Diabetes Free Review whopping $2.4 billion.The belief is that this will increase as there has been an observed increase in hospital admissions. And people with ongoing risk factors such as eating disorder and those that cannot afford insulin are more prone to such hospitalisation.Though DKA may be a symptom of undiagnosed diabetes, previously known sufferers may also come down with it as a result of several possible factors amongst which are poor compliance with insulin therapy or undercurrent illness.

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Where DKA results from undercurrent illness, the following symptoms, signs may be observed; coughing, fever, chills, chest pain, arthralgia, dyspnoea.So how does one go about diagnosing DKA? This is done with blood and urine tests which will tend to reflect high blood sugar and ketones respectively. In addition, on physical examination, the patient may be observed to have dry skin, decreased reflexes, ill appearance, acetone (ketotic) breath often described as "fruity", laboured respiration (kussmaul respiration), dry mucous membranes, decreased skin turgor and where the dehydration is severe enough to cause a decrease in the circulating blood volume, low blood pressure and tachycardia (a fast heart rate).

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